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Important Disclaimer
These statements have not been evaluated by the Food and Drug Administration (FDA). Compounded products are not FDA-approved and are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary. The information provided is for educational purposes only and should not be considered medical advice. Always consult with your healthcare provider before starting any new treatment.
Clinical Information
Evidence-based details for healthcare providers
Use as directed by your healthcare provider. Apply a thin, even layer to clean, dry, intact skin and cover if instructed. Do not use on broken skin or near eyes, mouth, or open wounds. If you forget to apply it before your appointment, tell your provider; do not apply extra gel or leave it on longer than directed.
Both lidocaine and tetracaine block tiny gates called sodium channels in your nerve endings. When these channels are blocked, pain signals cannot travel to your brain, so the area feels numb. Numbing usually starts within 20–30 minutes of application and can last 30–90 minutes after the gel is removed, depending on skin thickness and contact time.
Do not use if you are allergic to lidocaine, tetracaine, other local anesthetics, or any ingredient in this gel (may cause severe rash or swelling). Do not use on broken or infected skin because more drug could enter your bloodstream. Avoid if you have a history of methemoglobinemia (a blood disorder that lowers oxygen), severe liver disease, or certain heart rhythm problems. Not for infants under 6 months. Talk to your provider if you are pregnant or breastfeeding before use.
Using other local anesthetics (such as benzocaine sprays or dental numbing gels) at the same time can increase side effects. Class I anti-arrhythmics like mexiletine may raise blood levels of lidocaine and cause heart rhythm changes. Medicines that trigger methemoglobinemia (including nitrates, nitrites, sulfonamides, or the antibiotic dapsone) can add to blood problems. Tell your healthcare provider about all prescription drugs, over-the-counter drugs, vitamins, and herbal products, especially St. John’s wort and large amounts of alcohol, which may increase dizziness.
Very common (more than 1 in 10 people): temporary redness, mild swelling, or whitening where gel is applied; these usually fade within hours. Common (1–10 in 100 people): mild burning, tingling, or itching during or shortly after application. Uncommon (1–10 in 1,000 people): bruising, skin discoloration, small blisters. Rare but serious: dizziness, ringing in ears, irregular heartbeat, seizures, or gray/blue skin (signs of methemoglobinemia). Remove the gel and seek emergency help if you notice serious symptoms.
Store tightly closed at room temperature, 68-77 °F (20-25 °C). Keep away from heat, direct sunlight, and moisture. Do not freeze. Keep out of reach of children and pets. After opening, use within 6 months or as instructed. Dispose of leftover or expired gel through a pharmacy take-back program or mix with coffee grounds in a sealed bag before discarding in household trash.
Frequently Asked Questions
How long before my procedure should I apply the gel?
Most providers ask you to apply the gel 20–60 minutes before the procedure, but timing can vary. Follow the exact schedule your provider gives you.
Can I use this gel on broken skin or open wounds?
No. Using it on broken or irritated skin can let too much medicine into your bloodstream and increase side effects. Only apply to healthy, intact skin.
What should I do if my skin turns white or red after I remove the gel?
Mild color changes are normal and should fade within a few hours. If redness spreads, blisters form, or the area stays irritated for more than a day, call your healthcare provider.
Is it safe to drive after using this anesthetic gel?
The gel works only where it is applied and should not affect your thinking or reflexes. However, if you feel dizzy or light-headed, wait until you feel normal before driving.
Can I put a heating pad over the area to make it work faster?
No. Heat can make more drug enter your body and raise the risk of side effects. Keep the treated area at normal skin temperature unless your provider instructs otherwise.
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