Prescription
Prescription RequiredCompoundedBi-Est (80/20) Rapid Dissolving Tablet (RDT)
Biest Rapid Dissolving Tablet combines estradiol and estriol in an 80/20 ratio for hormone replacement therapy to manage symptoms of menopause such as hot flashes and vaginal dryness.
Requires a valid prescription from your provider. Not sure if it's right for you? Ask a pharmacist.
These statements have not been evaluated by the Food and Drug Administration. Compounded products are not FDA-approved and are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary. This information is for educational purposes only and is not medical advice — always consult your healthcare provider before starting any new treatment.
Clinical information
Medication information for patients and providers.
Dissolve 1 tablet in the mouth once daily, preferably at the same time each day. If you miss a dose, take it as soon as you remember. Do not take two doses at the same time. Duration of treatment should be as prescribed by your doctor.
This medication provides estrogen hormones to help manage menopause symptoms. Estradiol and estriol bind to estrogen receptors in the body, helping to relieve hot flashes and reduce vaginal dryness. Effects are usually noticed within a few weeks to months of consistent use.
Do not use if you have a history of breast cancer, blood clots, or liver disease. Do not use if you are pregnant or breastfeeding. Not recommended for individuals with a known hypersensitivity to estradiol or estriol.
Tell your doctor if you use thyroid medications or blood thinners like warfarin, since adjustments may be necessary. Avoid grapefruit juice and other citrus fruits that may affect hormone levels. Inform your healthcare provider about all other medications and supplements you are taking.
Common side effects may include nausea, breast tenderness, and headache. Less common side effects include mood changes, weight gain, and skin rashes. Contact your doctor if side effects are severe or persistent.
Store in a cool, dry place at 68-77°F (20-25°C). Keep in the original container to protect from light and moisture. Do not store in the bathroom. Dispose of any unused medication via a pharmacy take-back program.
Frequently asked questions.
Dissolve one tablet in your mouth daily at the same time each day. Follow your doctor's instructions for the duration of treatment.
Take the missed dose as soon as you remember. If it's close to the time for your next dose, skip the missed dose and continue your regular schedule.
No, Biest RDT is not for use if you are pregnant, as it may harm an unborn baby. Consult your doctor for alternatives.
Avoid grapefruit juice and other citrus products as they can interfere with hormone levels. Discuss dietary concerns with your healthcare provider.
You might experience nausea, breast tenderness, or headache. Report any unusual or severe symptoms to your doctor.
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