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Available Strengths (6)·Most prescribed
Active Ingredients
Important Disclaimer
These statements have not been evaluated by the Food and Drug Administration (FDA). Compounded products are not FDA-approved and are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary. The information provided is for educational purposes only and should not be considered medical advice. Always consult with your healthcare provider before starting any new treatment.
Clinical Information
Evidence-based details for healthcare providers
Dissolve 1 tablet in the mouth once daily, preferably at the same time each day. If you miss a dose, take it as soon as you remember. Do not take two doses at the same time. Duration of treatment should be as prescribed by your doctor.
This medication provides estrogen hormones to help manage menopause symptoms. Estradiol and estriol bind to estrogen receptors in the body, helping to relieve hot flashes and reduce vaginal dryness. Effects are usually noticed within a few weeks to months of consistent use.
Do not use if you have a history of breast cancer, blood clots, or liver disease. Do not use if you are pregnant or breastfeeding. Not recommended for individuals with a known hypersensitivity to estradiol or estriol.
Tell your doctor if you use thyroid medications or blood thinners like warfarin, since adjustments may be necessary. Avoid grapefruit juice and other citrus fruits that may affect hormone levels. Inform your healthcare provider about all other medications and supplements you are taking.
Common side effects may include nausea, breast tenderness, and headache. Less common side effects include mood changes, weight gain, and skin rashes. Contact your doctor if side effects are severe or persistent.
Store in a cool, dry place at 68-77°F (20-25°C). Keep in the original container to protect from light and moisture. Do not store in the bathroom. Dispose of any unused medication via a pharmacy take-back program.
Frequently Asked Questions
How should I take Biest RDT?
Dissolve one tablet in your mouth daily at the same time each day. Follow your doctor's instructions for the duration of treatment.
What if I forget to take my tablet?
Take the missed dose as soon as you remember. If it's close to the time for your next dose, skip the missed dose and continue your regular schedule.
Can I take Biest RDT if I'm pregnant?
No, Biest RDT is not for use if you are pregnant, as it may harm an unborn baby. Consult your doctor for alternatives.
Are there foods or drinks I should avoid?
Avoid grapefruit juice and other citrus products as they can interfere with hormone levels. Discuss dietary concerns with your healthcare provider.
What side effects should I expect?
You might experience nausea, breast tenderness, or headache. Report any unusual or severe symptoms to your doctor.
Related Products

Bi-Est (50/50) Cream
This compounded cream contains equal parts estradiol and estriol, two forms of estrogen. It is applied to the skin to help relieve symptoms of low estrogen such as hot flashes, night sweats, and vaginal dryness. Because this is a compounded medication, it is prepared by a licensed pharmacy for your individual needs and is not reviewed by the FDA for safety or effectiveness.

Bi-Est (80/20) Cream
Bi-Est Cream is a compounded hormonal therapy cream used for hormone replacement in women experiencing menopause symptoms. It contains a blend of two estrogens, estradiol and estriol, which help alleviate symptoms like hot flashes and vaginal dryness.

Estradiol Rapid Dissolve Tablets
Estradiol Rapid Dissolve Tablets supply bio-identical estrogen to ease common menopause symptoms like hot flashes, night sweats, mood swings, and vaginal dryness. The quick-dissolve design melts on your tongue without water, making daily dosing simple and comfortable.

Estradiol Cream
Estradiol Cream is a bio-identical hormone replacement therapy (BHRT) made for women who need extra estrogen. The cream uses an advanced base that helps the medicine pass through the skin evenly. It is most often prescribed to ease menopausal symptoms such as hot flashes, night sweats, and vaginal dryness.
