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Active Ingredients
Important Disclaimer
These statements have not been evaluated by the Food and Drug Administration (FDA). Compounded products are not FDA-approved and are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary. The information provided is for educational purposes only and should not be considered medical advice. Always consult with your healthcare provider before starting any new treatment.
Clinical Information
Evidence-based details for healthcare providers
Use this medication exactly as directed by your healthcare provider. This medicine is for use in the ear only unless your provider tells you otherwise. Wash your hands before and after use, and avoid touching the dropper tip to your ear or any surface. If you miss a dose, use it when you remember unless it is almost time for your next dose. Do not use extra to make up for a missed dose. Your healthcare provider will tell you how often to use it and how long to continue treatment.
Vancomycin is an antibiotic that kills certain bacteria by blocking the building of their protective outer wall. When used in the ear, it works mainly where it is placed, so it can help lower the amount of bacteria in the ear canal or nearby tissue. Some people may notice less drainage, pain, or irritation within a few days, but the full benefit depends on the type and severity of the infection. It is important to finish the full treatment time prescribed, because stopping too early may allow bacteria to remain and the infection may come back.
Do not use if you are allergic to vancomycin or any ingredient in the compounded solution. Do not use if your healthcare provider has not confirmed that this product is appropriate for your ear condition. Do not use in the eye, by mouth, or by injection. Do not use if you have severe ear pain, bleeding from the ear, sudden hearing loss, dizziness, or a known hole in the eardrum unless your ear specialist specifically tells you to use it, because some ear products may worsen irritation or injury in these situations. Tell your provider before use if you are pregnant, planning pregnancy, breastfeeding, have kidney disease, hearing problems, or are using other ear medicines.
Because this medicine is placed in the ear, whole-body drug interactions are expected to be lower than with oral or injected vancomycin, but interactions can still matter in some cases. Use caution with other medicines that may affect hearing or kidneys, especially aminoglycoside antibiotics such as gentamicin or tobramycin, loop water pills such as furosemide, and some strong antibiotics given by mouth or injection; the risk is more important if the eardrum is not intact or if you are also receiving vancomycin another way. Using other ear drops at the same time may change how well this medicine works or increase irritation, so ask your provider how to space them apart. There are no known food interactions with ear use. Alcohol does not directly interact, but heavy alcohol use may slow healing and worsen dehydration if you are ill.
Common side effects may include mild burning, stinging, fullness in the ear, itching, bad taste in the throat after use, or temporary mild irritation at the application site. These effects are often short-lived and may improve as your ear adjusts to treatment. Less common side effects include worsening redness, rash, increased drainage, headache, or discomfort that does not go away. Rare but serious reactions can include allergic reaction with swelling, hives, trouble breathing, severe rash, worsening hearing, ringing in the ears, severe dizziness, or balance problems. Stop using the medication and get medical help right away if you have signs of a serious allergic reaction or sudden hearing changes.
Store as directed on the pharmacy label. In general, compounded ear solutions are often kept refrigerated at 36-46 degrees F / 2-8 degrees C unless your pharmacist tells you otherwise. Keep the container tightly closed and protect it from heat, direct light, and contamination. Do not freeze. Do not store in the bathroom. Keep out of reach of children and pets. Because this is a compounded medication, use it only until the beyond-use date on the label, then discard any remaining product through your pharmacy if possible.
Frequently Asked Questions
What is vancomycin ear solution used for?
This compounded ear solution may be prescribed for certain bacterial ear infections when your healthcare provider feels vancomycin is an appropriate choice. It is not meant for viral or fungal infections unless your provider gives special instructions.
How soon will I feel better?
Some people notice less pain, drainage, or irritation within a few days. Even if you feel better early, keep using it for the full time prescribed unless your provider tells you to stop.
Can I use this if I have a hole in my eardrum or ear tubes?
Do not use it unless your ear specialist or prescribing provider specifically says it is safe for you. A damaged eardrum or ear tubes can change how the medicine reaches deeper parts of the ear.
What should I do if I miss a dose?
Use the missed dose when you remember unless it is almost time for your next dose. Do not use two doses at once, and do not use extra drops to make up for the missed dose.
Can I use other ear drops at the same time?
Only if your healthcare provider has told you to do so. If you are prescribed more than one ear medicine, ask your provider or pharmacist how many minutes to wait between products so each one can work properly.
What side effects mean I should call my doctor right away?
Call right away if you have worsening pain, more drainage, rash, swelling, ringing in the ears, hearing changes, severe dizziness, or balance problems. Get emergency help for trouble breathing or signs of a serious allergic reaction.
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