Clinical Information
Use as directed by your healthcare provider. Place the prescribed number of drops under your tongue and hold for at least 60 seconds before swallowing. If you miss a dose, take it as soon as you remember unless it is close to your next dose. Do not double up on doses. Your healthcare provider will determine how long you should stay on this medication.
Semaglutide copies the action of a natural gut hormone called GLP-1. It binds to GLP-1 receptors, which triggers your pancreas to release more insulin when blood sugar is high and tells your liver to make less sugar. It also slows stomach emptying and sends fullness signals to your brain, helping you eat less. Most people feel reduced appetite within the first week, but blood-sugar control and weight changes usually appear after 4–8 weeks of regular use. Each dose works for about 24 hours.
Do not use if you or a family member has ever had medullary thyroid cancer or multiple endocrine neoplasia syndrome type 2 (MEN 2) because it may raise the risk of thyroid tumors. Do not use if you are pregnant, planning to become pregnant, or breastfeeding, as safety is not established. Do not use if you are allergic to semaglutide or any ingredients in this suspension (may cause severe rash or swelling). Avoid if you have severe stomach or bowel disease like gastroparesis since the drug slows stomach emptying. Not approved for children under 18 years old.
Using semaglutide with insulin or sulfonylurea drugs (like glipizide, glyburide) may cause low blood sugar—check levels often and ask your provider about dose changes. It can slow absorption of oral medicines such as thyroid pills or antibiotics; take those at least 1 hour before semaglutide if possible. Combining with other GLP-1 agonists (exenatide, liraglutide) increases side effects and is not recommended. Warfarin levels may change—watch INR closely. Alcohol can increase risk of low blood sugar and stomach upset, so limit drinking. Tell your provider about all prescription drugs, over-the-counter medicines, vitamins, and herbal products you take.
Very common (more than 1 in 10 people): nausea, decreased appetite. Common (1–10 in 100 people): vomiting, diarrhea, constipation, stomach pain, headache, fatigue. Uncommon (1–10 in 1,000 people): gallstones, increased heart rate, injection-site reaction if combined with injectable GLP-1 drugs, mild dizziness. Rare but serious: pancreatitis (severe stomach pain that spreads to the back), kidney injury from dehydration, severe allergic reaction (rash, swelling of face or throat), thyroid tumors (lump or swelling in neck, hoarseness, trouble swallowing). Most stomach side effects improve after the first few weeks. Stop the drug and seek medical help right away if you get severe abdominal pain, yellow skin, or signs of an allergic reaction.
Store in the refrigerator at 36-46°F (2-8°C) in the original amber bottle to protect from light. Do not freeze. Keep the bottle tightly closed when not in use and avoid shaking. If refrigeration is not available, the suspension may be kept at room temperature (up to 77°F, 25°C) for a single period of up to 30 days, then discard any leftover. Keep away from children and pets. Dispose of unused or expired medicine through a pharmacy take-back program or mix with used coffee grounds in a sealed bag before throwing in household trash.
Frequently Asked Questions
Q:How do I take the drops correctly?
A:Use the dropper to place the prescribed number of drops under your tongue. Hold them there for at least 60 seconds without swallowing to let the medicine absorb, then swallow any leftover liquid.
Q:When will I start losing weight?
A:Most people notice a drop in appetite in the first week and begin to lose weight within 4–8 weeks, as long as they also follow a healthy eating and exercise plan. Full benefits build over several months.
Q:What should I do if I feel sick to my stomach?
A:Nausea is common at the start. Eat smaller meals, avoid greasy foods, and sip water during the day. If vomiting or severe nausea continues for more than a few days, call your healthcare provider.
Q:Can I drink alcohol while using semaglutide?
A:Limit alcohol because it can lower blood sugar and upset your stomach. If you choose to drink, do so in moderation and watch for signs of dizziness or low blood sugar such as sweating and fast heartbeat.
Q:Is this safe for someone with thyroid problems?
A:Do not use if you or a family member has had medullary thyroid cancer or MEN 2. If you have other thyroid issues, tell your provider so they can decide if semaglutide is right for you and monitor your condition.
Q:How should I store the bottle when I travel?
A:Keep the bottle in an insulated cooler with an ice pack to stay between 36-46°F (2-8°C). Do not let it freeze. Once opened, you may keep it at room temperature for up to 30 days if a fridge is not available.
Q:Can I take this with my other diabetes pills?
A:Yes, but some diabetes medicines like insulin or sulfonylureas may need dose changes to avoid low blood sugar. Check your glucose regularly and talk with your provider about any adjustments.
Q:What happens if I miss a dose?
A:Take it as soon as you remember unless it is close to your next scheduled dose. Never double the amount at one time. If you miss doses often, set reminders or speak with your provider for help.
Related Products
Alpha-Lipoic Acid Injection
Alpha lipoic acid, also known as ALA, provides the body with a powerful antioxidant that supports essential cellular functions and protects against damage. Alpha lipoic acid is naturally produced by the body and can be obtained from dietary sources. ALA injections are quickly absorbed and distributed throughout the major organs, supporting blood sugar levels and energy production.
L-Carnitine Injection
L-Carnitine Injection supplies a concentrated dose of the amino-acid–like nutrient L-carnitine. Your body uses L-carnitine to move fat into the parts of cells that burn it for energy. Healthcare providers may prescribe these injections to support weight-loss plans, boost exercise endurance, or help with certain metabolic conditions. This sterile solution is made for intramuscular or slow intravenous use under medical supervision.
Pyridoxine (Vitamin B6) | Methionine | Inositol | Choline Injection
Lipo Plus is a compounded lipotropic injection that combines Vitamin B6, methionine, inositol, and choline. These nutrients help the liver break down fats, support energy production, and aid normal metabolism. Healthcare providers often add Lipo Plus to weight-management plans that include a balanced diet and regular exercise. This sterile solution is for intramuscular use only and is prepared in a licensed compounding pharmacy following strict USP <797> standards.
Liraglutide Injection
Liraglutide is a compounded glucagon-like peptide-1 (GLP-1) receptor agonist used to help control blood sugar and support healthy weight loss in eligible adults. It is supplied as a sterile solution for once-daily subcutaneous (under-the-skin) injection.