Clinical Information
Take 1 capsule by mouth once daily at the same time each day, with or without food. If you miss a dose, take it as soon as you remember unless it's near the time of your next dose, in which case you should skip the missed dose. Do not take two doses at the same time.
Anastrozole works by blocking an enzyme called aromatase, which the body uses to make estrogen. Without this enzyme, estrogen levels decrease, which slows the growth of estrogen receptor-positive breast cancer cells. It may take a few weeks to start noticing improvements in symptoms.
Do not use if you are pregnant, planning to become pregnant, or breastfeeding, as it can harm the baby. Do not use if you are allergic to anastrozole or any ingredient in the capsules. Not recommended for premenopausal women or children.
Inform your doctor of all medications you are taking, especially estrogen-containing therapies, tamoxifen, or certain cholesterol-lowering drugs. Avoid grapefruit and grapefruit juice, as they can affect how anastrozole is metabolized.
Common side effects (affecting 1-10 in 100 people) include hot flashes, joint pain, weakness, and nausea. Less common side effects include bone pain and mood changes. Contact your doctor if you experience severe or persistent side effects.
Store at room temperature (68-77°F, 20-25°C) in a dry place. Keep in the original container, tightly closed. Avoid exposure to high heat or moisture. Dispose of expired or unused capsules properly, preferably through a pharmacy take-back program.
Frequently Asked Questions
Q:How long does it take to see results?
A:Most patients may notice some improvement in breast cancer symptoms after a few weeks of treatment, but complete effects may take longer. Regular doctor visits will help monitor your progress.
Q:What should I do if I miss a dose?
A:If you miss a dose, take it as soon as you remember, unless it's close to your next dose. In that case, skip it and continue with your schedule. Do not take two doses at the same time.
Q:Can I take this with other medications?
A:Discuss all medications, including over-the-counter drugs and supplements, with your doctor. Some cholesterol medications and estrogen-containing drugs can interact with anastrozole.
Q:What are the most common side effects and what should I do about them?
A:Common side effects include hot flashes and joint pain. These are usually mild and may lessen with time. If they persist or become troublesome, consult your doctor.
Q:Is Anastrozole safe during pregnancy?
A:Anastrozole should not be used during pregnancy, as it can harm the developing baby. If you become pregnant while taking anastrozole, inform your doctor immediately.
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