
Clinical Information
Use as directed by your healthcare provider. If you miss a dose, apply it as soon as you remember unless it is almost time for your next dose. Do not use two doses at the same time. Your healthcare provider will decide how long you should continue treatment.
Vitamin E is an antioxidant that protects and soothes skin cells. When placed inside the vagina, it forms a thin moisturizing layer that reduces dryness and irritation. Some vitamin E is absorbed and can help the tissue heal by lowering inflammation. Most women feel less dryness within 1–2 weeks, and benefits usually last as long as the cream is used.
Do not use if you are allergic to vitamin E or any ingredient in this cream. Do not use if you have unexplained vaginal bleeding or an active vaginal infection unless your healthcare provider says it is safe. Do not insert during the first 6 weeks after vaginal surgery or childbirth unless approved by your provider. Use caution if you have a bleeding disorder or take blood-thinning medicine, as vitamin E in large amounts can increase bleeding risk.
Because the cream is used locally, interactions are unlikely, but small amounts may be absorbed. High doses of vitamin E can enhance the effect of blood thinners such as warfarin (Coumadin), increasing bleeding risk. Tell your provider if you take aspirin, clopidogrel (Plavix), or herbal products like ginkgo or fish oil. Avoid using other vaginal products (like spermicides or antifungal creams) at the same time unless your provider advises; spacing them 2–3 hours apart may help.
Very common: mild leakage of cream (up to 30% of users), usually lessens with continued use. Common (may affect 1–10 in 100 people): temporary burning, itching, or warmth after application; light staining of underwear. Uncommon (1–10 in 1,000): vaginal spotting, rash around the vulva, headaches. Rare but serious: severe allergic reaction with swelling or hives—stop use and seek medical help right away. Most local side effects ease within minutes to hours.
Store at room temperature (68-77 °F, 20-25 °C). Keep the tube tightly closed and protect from excess heat, moisture, and direct light. Do not freeze. Keep out of reach of children and pets. Discard any unused cream 6 months after opening or by the labeled expiration date, whichever comes first. Return unused or expired product to a pharmacy take-back program or seal in a bag with coffee grounds before discarding in household trash.
Frequently Asked Questions
Q:How long will it take before I feel relief from dryness?
A:Many women notice softer, less dry tissue within the first week. Full comfort may take 2–4 weeks of regular use.
Q:Can I use this cream with condoms?
A:Oil-based creams like this can weaken latex condoms and raise the chance of breakage. Use non-latex (polyurethane or polyisoprene) condoms or avoid sexual activity for 12 hours after applying the cream.
Q:What if I accidently use more than the prescribed amount?
A:A single extra dose is unlikely to cause harm, but you may feel more leakage or mild irritation. Skip the next scheduled dose and return to your regular schedule. Call your provider if you feel severe discomfort.
Q:Is it safe to use while on blood thinners?
A:Small amounts of vitamin E may enter the bloodstream and could slightly increase bleeding risk. Let your healthcare provider know you use a blood thinner so they can monitor you.
Q:Can I use this cream during my period?
A:Yes, you can continue use, but some women prefer to pause because flow may wash out the cream sooner. Ask your provider what is best for you.
Q:How should I clean the applicator?
A:Wash the reusable applicator in warm soapy water after each use, rinse well, and let it air-dry completely before the next dose. Do not boil or use harsh cleaners.
Related Products

Alleviate (PMS Relief) IV KIT
The Alleviate (PMS Relief) IV KIT is designed to help ease symptoms associated with premenstrual syndrome by supplying vital electrolytes and vitamins. This kit includes: Calcium Chloride 100mg/ml, Magnesium Chloride 300mg/ml, Vitamin B1, B3 100mg, B2, B5, B6 2mg/ml, and Hydroxocobalamin B12 2mg/ml to help support nerve function and reduce cramps.

Clomiphene Tablets
Clomiphene tablets are prescription oral tablets used to help certain women who are not ovulating become pregnant. The medicine acts on the brain to trigger the release of hormones that start ovulation. Treatment is usually short-term and closely supervised by a healthcare provider.

Estradiol | Vitamin E Vaginal Cream
This compounded vaginal cream contains a low dose of estradiol (a form of estrogen) and vitamin E. It is designed to ease vaginal dryness, itching, and discomfort that can happen after menopause or certain medical treatments. The cream is applied inside the vagina where it helps restore moisture, improve tissue health, and make intimacy more comfortable. Your healthcare provider will decide how often and how long you should use it.

Diazepam Suppository
Diazepam vaginal suppositories are compounded medicine used to relax tight pelvic muscles and ease vaginal pain or spasms. Your healthcare provider may prescribe them for conditions like pelvic floor dysfunction, vaginismus, or painful intercourse. The suppository is placed inside the vagina where the medication is slowly absorbed, giving local muscle relaxation with only small amounts reaching the rest of the body.