Clinical Information
Use as directed by your healthcare provider. Apply a thin layer to clean, dry skin, usually once daily at night unless told otherwise. If you miss a dose, apply it when you remember unless it is almost time for your next dose. Do not apply two layers at the same time.
Retinoic acid speeds up the turnover of skin cells and boosts collagen, which can soften fine lines and fade dark spots. Hyaluronic acid pulls water into the upper skin layers, giving a plumper, smoother look. Ascorbic acid (vitamin C) is an antioxidant that helps even skin tone and protects against daily damage from sunlight and pollution. Most users start to see a brighter, smoother appearance within 4–8 weeks, with best results after 3–6 months of steady use.
Do not use if you are pregnant, trying to become pregnant, or breastfeeding because retinoic acid may harm an unborn baby. Do not use if you are allergic to retinoids, hyaluronic acid, vitamin C, or any cream ingredients. Avoid use on broken or severely irritated skin, eczema flares, or active sunburn. Not for children under 18 unless a healthcare provider decides it is needed.
Using other topical products that peel or dry the skin, such as benzoyl peroxide, salicylic acid, glycolic acid, or alcohol-based astringents, can raise the risk of redness and irritation—space them out or avoid them. Oral or topical antibiotics that increase sun sensitivity (like doxycycline) may add to sunburn risk; use extra sun protection. Products containing hydroquinone may increase skin dryness when layered with this cream. Tell your provider about all medicines, vitamins, and herbal supplements you use.
Very common (more than 1 in 10 people): mild redness, dryness, or peeling during the first few weeks—often improves with continued use and moisturizer. Common (1–10 in 100 people): stinging, itching, mild burning, or increased sun sensitivity. Uncommon (1–10 in 1,000 people): skin discoloration or swelling. Rare but serious: severe allergic rash, blistering, or eye irritation if applied too close to eyes—stop use and seek medical help right away. Most mild side effects settle in 2–4 weeks.
Store at room temperature (68–77 °F, 20–25 °C). Keep the cap tightly closed and protect from light, heat, and moisture. Do not freeze. Keep out of reach of children and pets. Discard any unused cream 6 months after first opening or by the expiration date, whichever comes first. Use a pharmacy take-back program or mix the leftover cream with coffee grounds in a sealed bag before throwing it away.
Frequently Asked Questions
Q:How soon will I see results?
A:Most people notice smoother, brighter skin in 4–8 weeks. Deeper changes like fading dark spots and fine lines can take 3–6 months. Keep using the cream daily for best results.
Q:Should I apply the cream in the morning or at night?
A:Night use is preferred because retinoic acid can break down in sunlight and may make skin more sun-sensitive. Apply to clean, dry skin before bed unless your provider tells you differently.
Q:Can I use makeup after applying the cream?
A:Yes. Let the cream fully absorb and follow with a gentle moisturizer. In the morning, wash your face, apply sunscreen, and then put on makeup as usual.
Q:What if my skin gets too dry or irritated?
A:Use a gentle, fragrance-free moisturizer and reduce application to every other night until your skin adjusts. If severe redness or pain occurs, stop use and contact your healthcare provider.
Q:Is it safe to use during pregnancy?
A:No. Retinoic acid may cause birth defects. Stop using the cream and talk with your doctor if you become pregnant or plan to become pregnant.
Q:Do I need to wear sunscreen while using this product?
A:Yes. Retinoic acid and vitamin C can make your skin more sensitive to sunlight. Apply a broad-spectrum SPF 30 or higher every morning, even on cloudy days.
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